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While electrophoretic mobility shift assays and mass spectrometry data both suggested a potential role of this mixed disulfide for catalysis 26 , kinetic assays later revealed the irrelevance for the catalytic cycle and thus confirmed that the Grx(SSR) species was an artifact 29
If not treated, intestinal obstructions could cause death of the surrounding tissue and infection of the abdominal cavity (peritonitis)
183 However, in vitro both of these mechanisms were not responsible for insulins drastic enhancement of cytotoxicity of the folic acid analog methotrexate to MCF-7 human breast cancer cells
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