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This approval is a significant decision because people living with excess weight or obesity and established cardiovascular disease and without diabetes have never had an FDA-approved treatment option that lowers weight and reduces the likelihood of another cardiovascular event, said A Michael Lincoff (Cleveland Clinic, Cleveland, USA) and the lead study author of the SELECT outcomes trial

Autistic symptom changes were not evaluated as part of the study, but children in both groups showed improvement in cysteine, plasma sulfate, and whole-blood glutathione levels

Second Natures programme combines medication support with personalised nutrition guidance from registered dietitians and nutritionists, built around a balanced plate of vegetables, protein, complex carbohydrates, and healthy fats

Rizo said