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The BALANCE model, which stands for Better Approaches to Lifestyle and Nutrition for Comprehensive hEalth, represented a structured attempt to provide GLP-1 access through government programs while controlling costs through direct manufacturer negotiation

Yet the substantia nigra dopaminergic neuron is also a metabolically stressed cell type whose autonomous activity, calcium handling, and large axonal arbor place unusual demands on linked purposeful movement, reinforcement, and cellular energetic support becomes progressively unstable

Li et al., 2024)

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