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Interestingly, in some cells of the ARC nucleus, it is also possible to find neuropeptide receptors (molecules with a role in the regulation of calorie intake) together with GIP-R, probably implicated in the regulation of food intake

Tirzepatide may contribute to low blood pressure in some situations, especially if blood pressure is already being treated with medication or if a person becomes dehydrated

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The encoded PL involves the pancreatic lipase gene (PNLIP), which primarily acts in the duodenum by hydrolyzing triglycerides into monoacylglycerols and fatty acids [17]