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Allulose and GLP-1 Secretion: What In Vitro and Animal Studies Reveal In vitro and rodent studies suggest allulose may trigger GLP-1 secretion from intestinal L-cells more robustly than glucose, possibly by modulating sweet taste receptors (TAS1R2/TAS1R3) or metabolic sensors

Monitoring for Common Side Effects During Dose Increases As doses go up, side effects like nausea, vomiting, stomach upset, or fatigue may appear