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5-Amino-1MQ is a substrate-mimetic inhibitor occupying the nicotinamide binding site, with a reported IC of 1.2 0.1 M (Neelakantan et al., J Med Chem, 2017)
0.25 to 0.5 mg Once or twice daily 4 to 8 weeks Subcutaneous, 1 to 2 inches from lateral epicondyle Moderate to severe lateral epicondylitis, chronic cases Starting with a conservative dose makes sense for most people
First in the methionine synthase reaction, homocysteine is converted to methionine allowing for the recycling of 5-methyl-tetrahydrofolate (THF) to N5,10 methylene-THF which is needed for the de novo synthesis of thymidylic acid and ultimately, for DNA formation
The absence of a bacteriostat in sterile water only allows for a one time use
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