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However, big pharma will still have the ability to charge premium prices for innovator molecules, especially those with higher efficacy (eg retatrutide) and those aimed at niche patient populations rather than the mass market (eg survodutide, which is targeting MASH endpoints in clinical trials)

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Graphical abstract Similar content being viewed by others Introduction Cardiovascular disease is the leading cause of mortality among patients with type 2 diabetes mellitus (T2DM) and remains one of the most prevalent health concerns worldwide [1]

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