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investigated the regulatory effect of epithalon on the production of melatonin and cortisol in senescent monkeys, finding that the peptide significantly stimulated melatonin synthesis, thus normalizing the circadian rhythm of cortisol secretion [11]

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Treatment of cells with a peptide containing only the HIV-TAT sequence, as well as a peptide where the HIV-TAT sequence was introduced into the N-terminus of p53 TAD PEP, resulted in a minimal induction of cell death (Figure

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