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It has been found that the nucleolus is not visible during mitosis at the end of prophase (the first phase of mitosis), when the nucleolar membrane breaks down [64, 65]

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However, it is important to note that whilst these mechanisms are promising, the specific application to binge eating disorder requires careful clinical evaluation, as this condition involves complex psychological, behavioural, and biological factors that extend beyond appetite regulation alone

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Part II: dysregulated inflammation drives immunopathology

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