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B12 is a vitamin that plays a crucial role in cognitive and nervous system functions
A deficiency in methionine synthase function arising from mutations in its gene, known as MTR, gives rise to what is termed a CblG defect
The Endocrine Society's 2020 position statement on compounded hormones and peptides emphasizes that "compounded preparations should be used only when an FDA-approved product is not available or is not suitable for a particular patient" [12]
[15] [18] For borderline results, additional tests such as methylmalonic acid, homocysteine, or holotranscobalamin may be considered
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