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MGF expression is significantly increased in muscle, bone, and tendon following damage from mechanical stimuli and in the brain and heart following ischaemia with expression preceding that of IGF-1Ea after injury, suggesting that the two alternative splice forms serve distinct and sequential roles in tissue research applications and repair
It functions as a dual GIP and GLP-1 receptor agonist to improve glycemic control in type 2 diabetes patients
However, in the various populations with steroid-induced dysglycemia, GLP-1 RAs have demonstrated efficacy in improving glycemic control and supporting weight reduction, with additional reported renal and cardiovascular benefits
In other words, patients on GLP-1 agonists were getting lighter but not markedly fitter in terms of heart/lung capacity
