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Research status Educational reference only
Intramuscular administration of vitamin B12 is often preferred for its rapid improvement in patients with severe deficiency or severe neurological symptoms
Dr Markku Lhteenvuo, a research director at the University of Eastern Finland, said: It is possible that, in addition to factors such as reduced alcohol consumption, weight loss-related improvements in body image, or relief associated with better glycaemic control in diabetes, there may also be direct neurobiological mechanisms involved, for example, through changes in the functioning of the brains reward system. Responding to the findings, experts urged caution, including Prof David Nutt, who is the head of the neuropsychopharmacology unit at Imperial College London and chair of the independent scientific committee Drug Science
Consequently, the reduced caloric intake achieved through appetite suppression now only matches the new, lower energy output level accurately
