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Contraindications GLP-1 medications are contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

Administer 500 mcg (15 units) every morning Morning timing is important: taking it earlier in the day helps avoid fatigue or sleep disruption Continue Phase 1 until you notice appetite suppression or other metabolic changes, which typically occurs within 2 to 3 days Once you observe those effects, move immediately to Phase 2

Combine resistance training (23/week) with regular aerobic activity to preserve muscle and enhance metabolic adaptations

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