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The chromatographic system used a binary solvent (water and methanol) system delivered as a gradient

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BNF-aligned regimens are as follows: Without neurological involvement: 1 mg three times a week for two weeks, then 1 mg every three months With neurological involvement: 1 mg on alternate days until no further improvement, then 1 mg every two months Patients with neurological symptoms should be managed promptly, as delays may affect the extent of recovery

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