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Tissue distribution of GLP-1R GLP-1 mediates its effects by binding to its receptor, the GLP-1R, which is a sevenfold transmembrane G-coupled receptor that increases levels of cAMP by activating adenylate cyclase (89, 95, 96)

I'm getting different answers for things, but in general, it looks like it can be anywhere from like 14 hours on the low end to up to 72 hours on the high end, like three days