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Monitor your energy levels and weight to avoid underfueling, and coordinate closely with your prescribing provider. During the first few weeks after switching: You might experience some mild digestive symptoms again, similar to when you first started semaglutide Your healthcare provider may want to monitor your blood sugar more closely if you have diabetes Your weight loss may temporarily slow as your body adjusts to the new medication Just like when you started semaglutide, you'll gradually increase your tirzepatide dose over several months until you reach the target maintenance dose that works best for you

Ultimately, patients who embrace this comprehensive strategy not only experience more profound initial weight loss but also gain a much higher likelihood of keeping the pounds off long-term

Diabetologia 60, 1577-1585

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