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Chloramphenicol is known to cause bone marrow suppression, especially when serum concentrations exceed 25 mcg/ml
Research-chemical status: compounds like 5-Amino-1MQ are typically sold for laboratory use only, not for human consumption
In mouse models of highfat dietinduced liver steatosis, it significantly inhibits hepatic NNMT activity, reduces NAM methylation, increases NAD+ and SAM levels, enhances mitochondrial fatty acid oxidation, reduces hepatic triglyceride and lipid accumulation, lowers lipotoxicity markers (e.g., malondialdehyde, transaminases), improves hepatocellular injury, and reverses steatosis
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