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Consistent with these data, we found that rotenone inhibited mTOR-mediated p70S6K and 4E-BP1 activity and triggered neuronal apoptosis, as detected by increased expression of cleaved-caspase-3 in vivo (Fig

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3.4.2 Statins HMG-CoA reductase inhibitors (statins) are cornerstone therapies for preventing and treating atherosclerotic cardiovascular disease

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Cell 79 , 315328 (1994)

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PolmanCHReingoldSCBarkhofFCalabresiPAClanetMCohenJAet al

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