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GH and IGF-1 directly affect growth plates
Appetite suppression is well-established at this stage, and meaningful weight loss is typically underway
injections of 100 nmol kg 1 GLP-1 ( n = 6 mice), 100 nmol kg 1 GLP-1MK-801 (Pen-linked) ( n = 6 mice) or vehicle (isotonic saline, n = 6 mice) for 7 days
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