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Abstract Obesity and Type 2 diabetes represent global health challenges, and there is an unmet need for long-lasting and effective pharmacotherapies
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Before we dive into the 'how,' let's clarify the 'what.' GLP-1 (glucagon-like peptide-1) receptor agonists are a class of medications that mimic a natural hormone your gut produces
it is also a major NAD + consumer with a lower K m than most NAD + -consuming enzymes 40 and is implicated in the decline of NAD + levels observed during aging and disease 50,51,52
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