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For semaglutide, the typical starting dose is 0.25 mg weekly, increasing to 0.5 mg after four weeks, then to 1 mg, 1.7 mg, and eventually the target dose of 2.4 mg
They may damage important biomolecules, including lipids, proteins, and DNA (Lobo et al., 2010)
Additionally, some animal studies suggested GIP promoted fat accumulation, raising concerns that GIP agonists might cause weight gain rather than loss
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