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Furthermore, myogenic progenitors derived from C9orf72 ALS patients displayed increased susceptibility to oxidative stress and dysregulation of mitochondrial genes, and these events were associated with mitochondrial abnormalities and toxicity (Lynch et al., 2019)
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Specifically, in experimental models utilizing carbon tetrachloride (CCl 4 ), a recognized hepatotoxic agent, GPS administration has been shown to markedly alleviate hepatic damage (Mihailovi et al., 2014
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