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In vitro, BPC 157 was shown to increase endothelial tube formation in human umbilical vein endothelial cells (HUVECs)
Over time, they can develop micro-cracks that trap bacteria and are difficult to clean
The field moved from single GLP-1 receptor agonism, to dual GIP/GLP-1 agonism, and then to adding a third receptor glucagon to capture an energy-expenditure lever on top of appetite and glucose control
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