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One trial had ~10% of users drop out for irritation was using a combination cream that also had 10% azelaic acid so the irritation likely wasn't from the glutathione

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Published 2024-5-28 Background: Thioredoxin domain-containing protein 12 (TXNDC12) is upregulated in a variety of tumours, including pancreatic cancer (PAAD), and its high expression is closely associated with poor prognosis

So I would presume, but I hope I'm wrong, that once you stop the GLP-1, the symptoms that got better would come back, but we are going to look at this