Common adverse reactions reported in over 5% of patients treated with semaglutide include: Nausea Vomiting Diarrhea Abdominal pain Constipation Call your healthcare provider immediately if you experience any signs of an allergic reaction, including wheezing, chest tightness, fever, itching, bad cough, blue skin color, severe behavioral problems, chest pain or pressure, fast heartbeat, severe dizziness, passing out, nervousness and excitability, severe headache, or fits or swelling of the face, lips, tongue, or throat, How to reduce semaglutide side effects Your provider may start your weekly injections at a low dose and gradually increase to the prescribed dosage to minimize potential side effects
The July 2025 study from researchers at the Mayo Clinic underscores how menopausal hormone therapy (MHT) may enhance the effectiveness of treatments like tirzepatide when used together by postmenopausal women with obesity, says Dr
Up to 24% mean body weight loss after 48 weeks
Long-term efficacy and safety are still being monitored