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These observations position the complex as a tool compound for studying tissue-remodelling and antioxidant pathways at the cellular level

Its potential as a selective estrogen-related receptor alpha (ERR) inverse agonist opens up formidable new avenues for studying exercise physiology, metabolism, and endurance

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These differences in structural plasticity or rigidity among the three receptors give clues to further optimize unimolecular agonists using complementary amino acids to target common regions of individual receptors and distinct sequences to confer receptor selectivity