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Lab and animal studies build on this as well, showing the extract reduces inflammatory signals, boosts a protein important for barrier health (filaggrin), and has anti-itch/antibacterial activity (including against C.acnes, the bacteria linked to breakouts)
Deo, Risk stratification using coronary artery calcium and potential benefit of semaglutide therapy: A costeffectiveness modelling study, Diabetes, Obesity and Metabolism, 10.1111/dom.70515, 28 , 4, (3229-3237), (2026)
Furthermore, the EMA has withdrawn the weight loss medication rimonabant, a selective cannabinoid type 1 receptor antagonist, due to its reported links to increased risks of depression and suicide [70]
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