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Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity
This combination makes it relevant not just for aesthetic outcomes but for the broader inflammatory burden that accelerates aging in metabolically active tissues
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Age-related decline in gastric acid production and intrinsic factor availability may reduce the bodys ability to absorb oral B12 and other nutrients, making IM delivery a practical alternative
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