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The pulsatile gonadorelin pump induces earlier spermatogenesis than cyclical gonadotropin therapy in congenital hypogonadotropic hypogonadism men

Protons (H + ) are pumped across the inner membrane to create an electrochemical gradient, and the energy released when the protons flow back into the mitochondrial matrix drives ATP synthesis by ATP synthase, converting ADP and inorganic phosphate (P i ) into ATP