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Normalization of metabolite levels further demonstrates that reversal of this trained state is feasible and supports the strategy of targeting metabolic pathways to eliminate maladaptive training

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The full Thymosin Beta-4 molecule, under the name RGN-259, has entered formal clinical trials for conditions including dry eye disease and cardiac recovery, which validates the underlying biological mechanism that TB-500 shares

doi: 10.3389/fphys.2015.00253, 74 NICOLS.TanturliM.MattiuzG.AntonelliA.BaccaniI.BonaiutoC.et al