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The cardiovascular phenomenon of endothelial dysfunction involves a series of structural and functional abnormalities, including abnormal secretory capacity and properties of the endothelium and impaired vascular tone, as well as an impaired endothelial barrier function

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This study was performed to evaluate this hypothesis

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Mechanism: These symptoms occur when blood vessels in the skin widen, allowing more blood to flow to the area

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It does not cause the same bone density loss, hot flashes, or mood disruption that characterizes estrogen-suppressive therapies

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