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The importance of the dendritic pool of mitochondria has been confirmed by the fact that in hippocampal neurons, the depletion of mitochondria in dendrites diminishes the number of synapses and spines [31]

Importantly, this catalytic tetrad is conserved among all the seleno-GPxs (GPx1, GPx2, GPx3, GPx4, and GPx6) characterized from human (Table 1

These data indicate that the uptake mechanism of nanocarriers was mediated by endocytosis

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