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SARS-CoV-2 infection generates massive ROS production and the excessive oxidative damage is responsible for cytokine storm, undermined immunity, tissue damage and severe lung disease causing ARDS and death (Silvagno et al., 2020)
IGFBP-3 is the major carrier protein for circulating IGF-1, and suppression has implications for endogenous IGF-1 bioavailability post-cycle
Berberine dosages have not been formally established, but clinical studies use a dose range between 500mg and 2,000mg daily
Evening of skin tone (weeks 4 to 10): GHK-Cus anti-inflammatory mechanism reduces the oxidative stress that drives post-inflammatory hyperpigmentation
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