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Compounded semaglutide injections typically remain stable for 28 days when stored at 28C (refrigerator temperature), though exact stability depends on formulation specifics provided by your compounding pharmacy

Expiration after first puncture: Most compounding pharmacies label multi-dose vials "discard 28 days after first use" or "discard 21 days after first use." This is conservative

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This strategy involves using two distinct classes of glucose-lowering medications simultaneously, each working through different mechanisms to improve glycaemic control and provide additional cardiometabolic benefits