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In addition, the application of exendin-4, a GLP-1RA in obese mice triggered by diet restores C1q/TNF-related protein 3 (CTRP3) expression in keratinocytes, thereby inhibiting STAT3 phosphorylation via lysosomal-associated membrane protein 1 (LAMP1) and alleviating the psoriatic symptoms induced by imiquimod treatment [204]
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Although these items showed both uniform and non-uniform DIF, the overall impact on total scale scores was negligible (Figure 1)
Yamamoto S, Deguchi K, Onuma M, et al
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