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Apr 2011;62(2):151-7
Tirzepatide (Mounjaro, Zepbound) is a dual GIP/GLP-1 receptor agonist with a slightly different mechanism
Average Weight Loss on Semaglutide In the main clinical trial that supported semaglutide's approval for weight management (the STEP 1 trial), adults who took the 2.4 mg weekly dose lost, on average, about 15% of their body weight over 68 weeks, compared with a much smaller amount in the placebo group
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