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Systemic depletion of l-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth
3.1.2 Hepatic First-Pass Metabolism Even if a small amount of GSH enters the bloodstream, it will be quickly taken up and metabolized by the liver
421 In addition to PD-1/PD-L1 and CTLA-4, other immune checkpoints, such as TIGIT and LAG-3, are being explored as targets for novel immunotherapies
Komatsu, M
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