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Future work using transgenic mice, viral-mediated gene knockdown and different drinking paradigms will be important to clarify the relationship between ghrelin signaling in the brain and alcohol consumption

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Cecal levels of Akkermansia muciniphila have been strongly correlated with physiological metrics including glycemia and insulinemia 89 , and Akkermansia has correlated negatively with obesity-related measures 90 and has been implicated in DIO prevention 91,92