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A researcher adding native IGF-1 to a serum-containing medium is therefore adding something whose free fraction is set by the binding-protein content of that particular batch of serum rather than by the amount weighed out
Its multifaceted roles extend to potential involvement in synapse maturation and the Ca(2+)-dependent exocytosis essential for sensory perception of smell in the olfactory bulb
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Drug Metab Dispos 39(12):22902297
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