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Acta Neurobiol Exp

Finally, we evaluate how approaching these pathologies from a network level is a necessary direction for translational future research

The variable weight value (VIP) in Orthogonal Partial Least Squares-Discriminant Analysis is a measure of the expression pattern of each metabolite, the explanatory ability and depth of influence on the categorical discrimination of samples in each group, to explore meaningful differential metabolites, and then use the T-test to verify whether the differential metabolites between groups are significant

The restoration of GSH involves the action of the NADPH-dependent enzyme, glutathione reductase