A 2025 study in Biomolecules found that NNMT inhibitor treatment "reduces body weight, white adipose tissue mass, total cholesterol, and adipocyte size in obese mice." These changes suggest cardiovascular benefit beyond simple weight loss
Investigators use these peptides as tools to study endocrine feedback loops, hormone signaling pathways, and downstream metabolic markers under controlled experimental conditions
If we understand the differences in the molecular mechanisms by which they stimulate their metabolism during defensive or autoimmune responses, then we can discover clues as to possible attack points for therapeutic agents regulating the immune response, he explained
Mischley LK, Lau RC, Shankland EG, Wilbur TK, Padowski JM