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About 1 in 100 patients develops severe constipation requiring prescription laxatives, dose reduction, or discontinuation

Mitochondrial-derived peptides (MDPs), encoded by mitochondrial DNA (mtDNA) sORFs, include potent metabolic regulators like MOTS-c (16 aa), which activates AMPK to enhance glucose metabolism and oxidative stress resistance 32 , and Humanin (24 aa), a cytoprotective agent that suppresses apoptosis by inhibiting BAX 33

Pavkov, D.J

In addition to weight loss, Saxenda may offer overweight or obese individuals other important health benefits too, including improvements in blood sugar control, blood pressure, cholesterol, and A1c levels