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Notably, the prevention and treatment of PIPN is an extremely urgent issue to be addressed in patients treated with Pt-based chemotherapy

[34] Sermorelin acts on the growth hormone releasing hormone receptor (GHRHr) in the pituitary to regulate cellular activities

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The body appears to adapt to both the delayed gastric emptying effects and the central nervous system appetite-suppressing signals, resulting in reduced nausea, vomiting, and other GI symptoms even as doses increase to therapeutic levels