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The clinician determines whether it is appropriate and provides an individualized treatment plan
During winter months, when natural light exposure decreases, many people experience disruptions in serotonin production that contribute to SAD symptoms
For long-term success, they should be combined with: Nutrition counseling to support a sustainable dietary pattern Exercise and physical therapy to strengthen the back and core Behavioral coaching to build lasting habits Additionally, patients should avoid the temptation of using GLP-1 medications as a quick fix or without medical supervision
For example, CircABCB10 inhibits ferroptosis and apoptosis of rectal cancer cells by regulating the miR-326/CCL5 axis, providing a potential therapeutic target for the treatment of rectal cancer [138]
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