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Stomach acid denatures protein structures
Ms Danya Almheiri United Arab EmiratesICDS/10CP/Doc.6 Annex III 48 Global Task Force Team 7
While we cannot reproduce clinical photographs from the cited studies without permission, we can describe what the published cases document: Patil and Mitra (2026) describe tongue hyperpigmentation in the context of Addison's disease - typically presenting as diffuse darkening of the tongue surface, often alongside pigmentation of other mucosal surfaces and skin creases
10.1212/CON.0000000000000943 151
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