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Most clinicians recommend waiting until you've reached your target maintenance dose before making schedule changes, because the ramp-up phase requires precise timing to build tolerance

If you have prediabetes or metabolic syndrome, this transition period requires careful monitoring

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FAS inhibitors, such as C75, also activate the mechanistic target of rapamycin (mTOR), and since mTOR and AMPK activities are inversely related they are likely to be reciprocally involved in the regulation of appetite