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When comparing methylcobalamin vs cyanocobalamin, cyanocobalamin is widely used as it is generally considered more cost-effective
[37] The MMACHC gene product is characterised as a cyanocobalamin reductase (cyanide-eliminating) and an alkylcobalamin reductase
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It has also been said not to raise IGF-1 levels, which helps reduce worries about cancer risks
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