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The long-term effects of off-label use of GLP-1 medications for non-obese younger adult patients without type 2 diabetes remain unclear

ROS dysregulation in cardiovascular diseases ROS dysregulation represents a central node in cardiovascular diseases progression [314], involving endothelial dysfunction [315], cardiomyocyte injury [316], mitochondrial [317] and endoplasmic reticulum stress [318], vascular remodeling [319], and atherosclerosis [320]

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