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Semaglutide is a GLP-1 receptor agonist, while tirzepatide targets both GLP-1 and GIP receptors, which may provide additional appetite control and metabolic support depending on the patient

Metformin is available in a generic version, making it one of the most affordable prescription medications on the market

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Type 2 diabetes can be challenging enough to manage without the added risk of chronic kidney disease, and I have seen in my own practice that patients with type 2 diabetes and chronic kidney disease need extra support from medications that may have a profound clinical impact by lowering the risk of major kidney and cardiovascular outcomes, said Richard E Pratley (AdventHealth Diabetes Institute, Orlando, USA) co-chair of the FLOW trial