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A consistent estimation of the causal effect can be obtained using the weighted median method if the weighted median of the SNP-specific estimates reaches 50% (Verbanck et al., 2018)

Flow cytometry was employed to measure the DNA content of cells in the G 0 /G 1 , S, and G 2 /M phases

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Among them, the best known ROS in human cells include superoxide anion (O 2 - ), which is the precursor of most other ROS, hydroxyl radical ( OH), peroxyl radical (ROO ), hydroperoxyl radical ( HO 2 ), and hydrogen peroxide (H 2 O 2 ), although the last one is not technically a free radical because it does not have unpaired electrons, but it represents a source of them [25] (Fig